
Growth Hormone
Excessive
secretion of pituitary growth hormone has been seen in a few patients with
McCune-Albright syndrome. Most of these have been diagnosed as young adults,
when they developed the coarsening of facial features, enlargement of hands and
feet, and arthritis characteristic of the condition termed acromegaly. Therapy
has included surgical removal of the area of the pituitary which is secreting
the hormone, and the use of new, synthetic analogs of the hormone somatostatin,
which suppress growth hormone secretion.
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